NUMS — Medical & Dental Entry Test

NUMS Biology — Homeostasis, Support and Movement (Set 2)

Take the NUMS Biology — Homeostasis, Support and Movement (Set 2): 30 multiple-choice questions (40 minutes) with instant scoring and a full answer…

What this test covers

Sample questions with answers

The first 5 questions of this test, with the correct answer and explanation.

  1. Q1. Marine bony fish live in water saltier than their body fluids. To osmoregulate they:

    • A. Store urea in their blood like sharks
    • B. Drink seawater, excrete salts through gills and produce little urine ✓
    • C. Absorb salts through gills and excrete dilute urine
    • D. Drink no water and produce large volumes of dilute urine

    Answer: B. Drink seawater, excrete salts through gills and produce little urine

    Explanation: Marine teleosts lose water by osmosis, so they drink seawater, actively secrete excess salt from gill chloride cells, and make small amounts of concentrated urine.

  2. Q2. Freshwater fish face the problem of water entering their bodies by osmosis. They respond by:

    • A. Producing very concentrated urine
    • B. Drinking large amounts of water
    • C. Excreting salt through the gills
    • D. Producing large volumes of dilute urine and actively absorbing salts at the gills ✓

    Answer: D. Producing large volumes of dilute urine and actively absorbing salts at the gills

    Explanation: Freshwater is hypotonic to the fish, so they remove excess water as copious dilute urine and take up ions actively at the gills.

  3. Q3. The functional unit of the kidney is the:

    • A. Nephron ✓
    • B. Glomerulus alone
    • C. Ureter
    • D. Renal pelvis

    Answer: A. Nephron

    Explanation: Each kidney contains about a million nephrons, each performing filtration, reabsorption and secretion.

  4. Q4. The efferent arteriole leaving the glomerulus is narrower than the afferent arteriole entering it. This arrangement:

    • A. Lowers glomerular pressure to prevent filtration
    • B. Raises the hydrostatic pressure in the glomerulus, driving ultrafiltration ✓
    • C. Allows red blood cells to be filtered
    • D. Increases reabsorption of water in the loop of Henle

    Answer: B. Raises the hydrostatic pressure in the glomerulus, driving ultrafiltration

    Explanation: Blood enters faster than it can leave, so pressure builds up in glomerular capillaries and forces fluid into Bowman's capsule.

  5. Q5. About 65–80% of the filtered water and Na⁺, and nearly all of the filtered glucose and amino acids, are reabsorbed in the:

    • A. Bowman's capsule
    • B. Collecting duct
    • C. Proximal convoluted tubule ✓
    • D. Distal convoluted tubule

    Answer: C. Proximal convoluted tubule

    Explanation: The PCT, with microvilli and many mitochondria, reabsorbs all glucose and amino acids and most of the water and salts.

The other 25 questions

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  1. Q6. The glomerular filtration rate is 125 cm³ per minute and urine is produced at 1 cm³ per minute. What percentage of the filtrate is reabsorbed?

    • A. 99.2%
    • B. 92.0%
    • C. 80%
    • D. 12.5%
  2. Q7. Aldosterone acts on the distal tubule and collecting duct. A patient with an adrenal tumour secreting excess aldosterone would most likely show:

    • A. Glucose in the urine
    • B. Increased Na⁺ retention, high blood pressure and low blood K⁺
    • C. Large volumes of dilute urine
    • D. Low blood pressure and high blood K⁺
  3. Q8. ADH increases water reabsorption in the collecting duct by:

    • A. Inserting aquaporins into the membranes of duct cells
    • B. Increasing glomerular filtration
    • C. Actively pumping water out of the duct
    • D. Making the duct impermeable to urea
  4. Q9. Drinking alcohol causes increased urine output because alcohol:

    • A. Stimulates aldosterone secretion
    • B. Increases the number of nephrons
    • C. Blocks glomerular filtration
    • D. Inhibits ADH release from the posterior pituitary
  5. Q10. In the loop of Henle, the descending limb is permeable to water. As filtrate moves down it into the medulla, the filtrate becomes:

    • A. Unchanged in concentration
    • B. More dilute, because salts are pumped out
    • C. More concentrated, because water leaves into the salty medulla
    • D. Free of urea
  6. Q11. Urea is produced in the liver from:

    • A. Glucose and oxygen
    • B. Fatty acids and glycerol
    • C. Uric acid and water
    • D. Ammonia and carbon dioxide
  7. Q12. Freshwater fish and tadpoles can excrete nitrogenous waste as ammonia because:

    • A. Ammonia is non-toxic
    • B. They have no kidneys
    • C. Plenty of water is available to dilute and wash away the toxic, soluble ammonia
    • D. Ammonia needs no water to excrete
  8. Q13. In kidney transplantation, the recipient is given immunosuppressant drugs for life. This is because:

    • A. The new kidney cannot filter without them
    • B. They increase urine production
    • C. The immune system recognises the donor kidney's antigens as foreign
    • D. They prevent kidney stones
  9. Q14. A person enters a very hot room. Which combination of responses would the hypothalamus bring about?

    • A. Vasodilation and shivering
    • B. Vasodilation of skin arterioles and increased sweating
    • C. Vasoconstriction and increased sweating
    • D. Vasoconstriction and shivering
  10. Q15. Animals such as lizards that regulate body temperature mainly by behaviour (basking or seeking shade) are called:

    • A. Endotherms
    • B. Homeotherms
    • C. Heterotrophs
    • D. Ectotherms
  11. Q16. Fever during infection is caused by chemicals called pyrogens which:

    • A. Raise the set point of the hypothalamic thermostat
    • B. Destroy sweat glands
    • C. Block the thyroid gland
    • D. Lower the metabolic rate
  12. Q17. Which of the following is an example of negative feedback?

    • A. A rise in blood glucose leads to insulin release, which lowers blood glucose
    • B. An action potential opening more Na⁺ channels
    • C. Oxytocin stimulating stronger uterine contractions
    • D. Blood clotting factors activating more clotting factors
  13. Q18. Under the microscope, the dark A-band of a skeletal muscle sarcomere corresponds to the:

    • A. Length of the thick (myosin) filaments
    • B. Region containing only actin
    • C. Space between two sarcomeres
    • D. Z-line
  14. Q19. During contraction of a skeletal muscle sarcomere, which pair of measurements both decrease?

    • A. Length of the I-band and the H-zone
    • B. Length of the A-band and the I-band
    • C. Length of the myosin and actin filaments
    • D. Length of the A-band and the H-zone
  15. Q20. In the cross-bridge cycle, ATP is needed for:

    • A. Shortening of the actin filaments
    • B. Release of acetylcholine only
    • C. Attachment of calcium to myosin
    • D. Detachment of myosin heads from actin and re-cocking the head
  16. Q21. When calcium binds to troponin, contraction can begin because:

    • A. Tropomyosin shifts, exposing myosin-binding sites on actin
    • B. Myosin heads detach from actin
    • C. ATP is synthesised by troponin
    • D. Actin filaments shorten
  17. Q22. Smooth muscle differs from skeletal muscle because it is:

    • A. Multinucleated and striated
    • B. Branched with intercalated discs
    • C. Voluntary and striated
    • D. Involuntary, unstriated and made of spindle-shaped uninucleate cells
  18. Q23. During prolonged vigorous exercise, muscles fatigue. One main cause is:

    • A. Excess oxygen in the muscle
    • B. Loss of all calcium from the blood
    • C. Accumulation of lactic acid and depletion of ATP and glycogen
    • D. Increase in the number of muscle fibres
  19. Q24. Tendons connect:

    • A. Cartilage to skin
    • B. Muscle to bone
    • C. Nerve to muscle
    • D. Bone to bone
  20. Q25. The elbow and knee are examples of hinge joints. The joint between the atlas and the axis vertebrae that allows the head to turn side to side is a:

    • A. Hinge joint
    • B. Pivot joint
    • C. Gliding joint
    • D. Ball-and-socket joint
  21. Q26. In osteoarthritis, the joint becomes painful and stiff mainly because:

    • A. Articular cartilage wears away so bones rub together
    • B. Uric acid crystals form in the joint
    • C. Bone marrow stops making blood
    • D. Ligaments become too elastic
  22. Q27. Bone-forming cells that secrete the matrix of bone are called:

    • A. Osteoclasts
    • B. Chondrocytes
    • C. Osteoblasts
    • D. Fibroblasts
  23. Q28. A broken bone heals faster in a child than in an elderly person. Which is the best explanation?

    • A. Children have more active osteoblasts and a better blood supply to bone
    • B. Elderly people have more osteoblasts
    • C. Children's bones contain no calcium
    • D. Children have no osteoclasts
  24. Q29. Wood is strong and rigid mainly because xylem vessels and fibres have walls thickened with:

    • A. Suberin
    • B. Lignin
    • C. Cutin
    • D. Pectin
  25. Q30. When a plant is not watered for several days, its leaves wilt because:

    • A. Lignin is broken down
    • B. Chlorophyll is destroyed
    • C. Phloem stops transporting sugar
    • D. Cells lose turgor pressure