NUMS — Medical & Dental Entry Test

NUMS Biology — Biodiversity: Viruses, Bacteria and Kingdoms (Set 1)

Take the NUMS Biology — Biodiversity: Viruses, Bacteria and Kingdoms (Set 1): 30 multiple-choice questions (40 minutes) with instant scoring and a full…

What this test covers

Sample questions with answers

The first 5 questions of this test, with the correct answer and explanation.

  1. Q1. Viruses are often described as being at the borderline of living and non-living because they:

    • A. Can reproduce only inside living host cells and are inert outside them ✓
    • B. Respire aerobically outside cells
    • C. Divide by binary fission
    • D. Have their own ribosomes but no genetic material

    Answer: A. Can reproduce only inside living host cells and are inert outside them

    Explanation: Viruses lack metabolism and cell structure; they crystallise outside cells but replicate using host machinery inside cells.

  2. Q2. HIV is classified as a retrovirus because it:

    • A. Infects only bacteria
    • B. Uses reverse transcriptase to make DNA from its RNA genome ✓
    • C. Replicates without integrating into host DNA
    • D. Contains double-stranded DNA

    Answer: B. Uses reverse transcriptase to make DNA from its RNA genome

    Explanation: Retroviruses carry RNA and reverse transcriptase, converting RNA → DNA, which integrates into the host genome as a provirus.

  3. Q3. HIV causes immunodeficiency mainly because it destroys:

    • A. Red blood cells
    • B. B lymphocytes only
    • C. Platelets
    • D. Helper T (CD4⁺) lymphocytes ✓

    Answer: D. Helper T (CD4⁺) lymphocytes

    Explanation: HIV's gp120 binds CD4 on helper T cells; their loss cripples both humoral and cell-mediated immunity.

  4. Q4. In the lysogenic cycle of a bacteriophage:

    • A. The virus makes RNA from DNA using reverse transcriptase
    • B. The viral DNA integrates into the bacterial chromosome as a prophage and is replicated with it ✓
    • C. The host cell bursts immediately to release new phages
    • D. The phage injects its protein coat into the bacterium

    Answer: B. The viral DNA integrates into the bacterial chromosome as a prophage and is replicated with it

    Explanation: In lysogeny phage DNA integrates as a prophage and is passed to daughter cells until induced to enter the lytic cycle.

  5. Q5. A bacteriophage injects which part into the host bacterium during infection?

    • A. Its entire capsid and tail
    • B. Its tail fibres
    • C. Its nucleic acid only ✓
    • D. Its protein coat only

    Answer: C. Its nucleic acid only

    Explanation: The tail sheath contracts and the DNA is injected; the protein coat remains outside (as shown by Hershey–Chase).

The other 25 questions

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  1. Q6. Which statement about viral capsids is correct?

    • A. They are made of peptidoglycan
    • B. They contain ribosomes
    • C. They are lipid bilayers derived from the host nucleus
    • D. They are made of protein subunits called capsomeres
  2. Q7. A bacterium stains purple in the Gram stain. This indicates it has:

    • A. A thin peptidoglycan layer and an outer lipopolysaccharide membrane
    • B. A cell wall made of chitin
    • C. No cell wall at all
    • D. A thick peptidoglycan layer without an outer membrane
  3. Q8. Penicillin is effective against many bacteria because it:

    • A. Destroys bacterial ribosomes
    • B. Inhibits cross-linking of peptidoglycan during cell wall synthesis
    • C. Dissolves the bacterial plasma membrane
    • D. Blocks reverse transcriptase
  4. Q9. Why is penicillin generally more effective against Gram-positive than Gram-negative bacteria?

    • A. Gram-positive bacteria have an outer lipopolysaccharide layer
    • B. Gram-negative bacteria have thicker peptidoglycan
    • C. The outer membrane of Gram-negative bacteria hinders penicillin from reaching the peptidoglycan
    • D. Gram-positive bacteria lack a cell wall
  5. Q10. Bacterial endospores allow survival in harsh conditions because they:

    • A. Are a method of sexual reproduction
    • B. Carry out photosynthesis
    • C. Are dormant structures with tough coats resistant to heat and dryness
    • D. Reproduce rapidly in boiling water
  6. Q11. Transfer of genetic material between two bacteria through a pilus is called:

    • A. Transformation
    • B. Conjugation
    • C. Binary fission
    • D. Transduction
  7. Q12. Griffith found that heat-killed virulent pneumococci mixed with live harmless bacteria killed mice. The harmless bacteria had undergone:

    • A. Conjugation
    • B. Transduction
    • C. Transformation
    • D. Mutation by radiation
  8. Q13. Spherical bacteria arranged in grape-like clusters are called:

    • A. Streptococci
    • B. Staphylococci
    • C. Bacilli
    • D. Spirilla
  9. Q14. Cyanobacteria are placed in Kingdom Prokaryotae (Monera) although they photosynthesise, because they:

    • A. Have 80S ribosomes
    • B. Contain mitochondria
    • C. Have cellulose cell walls
    • D. Lack a membrane-bound nucleus and chloroplasts
  10. Q15. Heterocysts in cyanobacteria such as Nostoc are specialised for:

    • A. Movement
    • B. Asexual spore production
    • C. Storing starch
    • D. Nitrogen fixation
  11. Q16. In the five-kingdom system, organisms that are eukaryotic, mostly unicellular and include algae and protozoa belong to:

    • A. Plantae
    • B. Fungi
    • C. Monera
    • D. Protoctista
  12. Q17. Fungi are not classified as plants mainly because they:

    • A. Lack a nucleus
    • B. Have cell walls made of cellulose
    • C. Are heterotrophic and have cell walls made of chitin
    • D. Are always unicellular
  13. Q18. A fungus that obtains nutrients from dead organic matter by secreting digestive enzymes outside its body is a:

    • A. Mutualist
    • B. Saprotroph
    • C. Predator
    • D. Parasite
  14. Q19. The association between fungal hyphae and plant roots that improves mineral uptake is called:

    • A. Haustorium
    • B. Mycorrhiza
    • C. Root nodule
    • D. Lichen
  15. Q20. A lichen is a mutualistic association between:

    • A. A virus and a bacterium
    • B. A fungus and an alga or cyanobacterium
    • C. A fungus and a plant root
    • D. A bacterium and a legume
  16. Q21. Two organisms belong to the same order but different families. Which statement must be true?

    • A. They belong to the same class and phylum
    • B. They belong to different kingdoms
    • C. They belong to the same genus
    • D. They belong to different classes
  17. Q22. Which sequence of taxonomic ranks is in the correct descending order?

    • A. Kingdom, phylum, class, order, family, genus, species
    • B. Kingdom, class, phylum, family, order, genus, species
    • C. Phylum, kingdom, class, order, family, species, genus
    • D. Kingdom, phylum, order, class, genus, family, species
  18. Q23. Which disease is caused by a virus rather than a bacterium?

    • A. Hepatitis B
    • B. Tuberculosis
    • C. Cholera
    • D. Typhoid
  19. Q24. Hepatitis B is most commonly transmitted through:

    • A. Contaminated blood, sexual contact and mother to child
    • B. Contaminated food and water only
    • C. Mosquito bites
    • D. Inhalation of droplets
  20. Q25. Antibiotics are ineffective against the common cold because:

    • A. Cold viruses have thick peptidoglycan walls
    • B. Viruses are too large to be affected
    • C. Viruses lack the cell walls, ribosomes and metabolic pathways that antibiotics target
    • D. Antibiotics only work on fungi
  21. Q26. Prions differ from viruses in that prions:

    • A. Contain only RNA without a capsid
    • B. Contain DNA but no protein
    • C. Are infectious proteins with no nucleic acid
    • D. Are bacteria lacking a cell wall
  22. Q27. Bacteria which can grow with or without oxygen are termed:

    • A. Facultative anaerobes
    • B. Obligate anaerobes
    • C. Microaerophiles
    • D. Obligate aerobes
  23. Q28. Under ideal conditions a bacterium divides every 20 minutes. Starting from one cell, how many cells are present after 2 hours?

    • A. 32
    • B. 128
    • C. 64
    • D. 12
  24. Q29. A virus that has an envelope derived from the host cell membrane typically acquires it when:

    • A. Its DNA integrates into the host genome
    • B. It is assembled in the nucleolus
    • C. It buds out through the host plasma membrane
    • D. It enters the host by endocytosis
  25. Q30. The structure in some bacteria that helps them resist phagocytosis by white blood cells is the:

    • A. Capsule
    • B. Mesosome
    • C. Plasmid
    • D. Flagellum